תקציר סמינריון Posttraumatic stress disorder (PTSD) is a psychiatric disorder that locked in the group of anxiety disorders. The disorder may develop after exposure to a severe stressful experience or traumatic event (criterion A in the DSM diagnostic criteria). The most common causes to this disorder are: person that is seriously injured, witnesses death or serious injury to others, or experiences the threat of death or serious injury.
Combat exposure, personal assault, terrorism, automobile accidents, and natural disasters. The intense trauma produces vivid memories that don’t stop lasting.
Those memories can be triggered by a stimulus that associated with the original traumatic event (Cohen, Kozlovsky, Alona, Matar & Joseph, 2011).
Contest Introduction………………………………………………………………………………3
Material and Methods…………………………………………………………………….7
Animals…………………………………………………………………..……7
Procedure……………..…………………………………………………-…7
              Drug treatment……………………………………………………………..…8
    Behavioral Tests………………………………………………………….……9
Fear Conditioning……………………………………………………………..9
 Open Field Test………………………………………………………….……9
Sucrose Preference Test (SPT)………………………………….……….……9
Pre-Pulse Inhibition (PPI) and Startle Response)…………………….……..10 Social Interaction……..…………………….…………….…………………11
Porsolt Test………………………………………………………….………11
Statistical Analysis…………………………………………………..………12
Results ………………………………………………………………………….………13
Discussion and Conclusions ……………………………………………………………39
References ………………………………………………………………………………45